Use the Friction Block ($5.29 at Target) at the first sign of blisters. I usually have one in my purse for emergencies. If you're carrying a purse that's too small for such practicalities, and its too late, use the Blister Band-Aid ($3.69, also at Target. There's also a generic version, but I figured I would try the brand first). The Blister Fingers and Toes promises instant relief (this part is true) and faster healing (its my first try, so I don't know what "faster" is yet). Your feet will thank me later!